Sunday, August 5, 2012

FUTURE LAB MEMBERS

Hi,
you are keen on performing research on neuronal development, regeneration or degeneration? 
Let me know what you would like to do or come by to see and chat about what we currently are investigating.
Email or call me if you are interested in joining our lab.
cheers
Mike

PEOPLE | ROBERT MÜNCH


Tuesday, January 31, 2012

GROUP SNAPSHOT 01/2012 | LAB MOVE

Thanks to all lab members and CRTD staff for a successful move.

We are now located in the new CRTD building.
Lab address: CRTD, MOKALAB, 2nd floor north, Fetscherstrasse 105, 01307 Dresden, Germany.



Dr. Mike O. Karl
Research Group Leader
Retinal Development & Regeneration

Technische Universität Dresden
DFG-Center for Regenerative Therapies Dresden & Cluster of Excellence
MOKALAB 2nd FLOOR
Fetscherstraße 105
01307 Dresden
Germany

Phone (office): +49-351-458-82205
Phone (lab): +49-351-458-82236
Phone (technician): +49-351-458-82213

Fax: +49-351-458-6303
mike.karl@crt-dresden.de

http://www.crt-dresden.de/research/crtd-core-groups/karl/
http://www.mokalab.org
http://www.visionclub.org



Friday, January 20, 2012

NEWS | TIME TO MOVE

Dear MTZ colleagues and friends, its been a fun, friendly and fruitful time and we thank you for hosting us at the MTZ. A special thanks goes to the Dept. of Anatomy for their great support and kind help in all circumstances. Its time to pack up and move to our new space at the recently finished CRTD building.
Packing up MOKALAB at MTZ:

Wednesday, October 26, 2011

USEFUL HOMEPAGES

RETINA
http://webvision.med.utah.edu
http://www.fmi.ch/roska.data/index.php
http://www.gensat.org/retina.jsp

BRAIN ATLAS
http://www.brain-map.org
http://www.med.harvard.edu/aanlib/home.html
http://www.mbl.org/mbl_main/atlas.html


OTHERS
http://www.gensat.org/index.html
http://networkglia.eu/tiermodelle
http://www.ics-mci.fr/mousecre/
http://www.stjudebgem.org
https://syllabus.med.unc.edu/courseware/embryo_images/unit-welcome/welcome_htms/contents.htm

SOFTWARE
http://fiji.sc
http://www.openmicroscopy.org

BOOKS

http://www.currentprotocols.com/WileyCDA/CurPro3Title/isbn-0471142727,descCd-overview.html


Thursday, September 1, 2011

PEOPLE | ANNA SEIFERT

After I have finished my master studies in “Molecular Bioengineering”, I have joined the lab in August 2011 and work now on reprogramming of Müller glia cells using retroviral vector systems.

Wednesday, August 31, 2011

PEOPLE | MANUELA VÖLKNER

In Summer 2011 I successfully finished my Bachelor studies in the lab studying retinal development and regeneration. Currently, I am pursuing a masters degree at the CRTD RegBioMed program.

Monday, August 15, 2011

NEW LAB LOCATION @ DZNE 2011

DZNE SITE
We recently started our lab at the DZNE.


Dr. Mike O. Karl
Research Group Leader
Retinal Regeneration & Degeneration

Technische Universität Dresden
DZNE - German Center for Neurodegenerative Diseases
Arnoldstrasse 18 / 18b
01307 Dresden, Germany

mike.karl@dzne.de

http://www.mokalab.org
http://www.visionclub.org
http://www.dzne.de

Sunday, October 17, 2010

PEOPLE | SHEIK PRAN BABU SARDAR PASHA

Sheik Pran Babu Sardar Pasha (M.Tech, B.Tech)

Last year I wrote with Mike an successful application for a competitive DAAD fellowship (Sandwich Model Fellowships for Ph. D. Registered Scholars). This stipend allows me to extend my PhD studies that I started in the lab of Dr. G. Sangiliyandi at the Dept. of Biotechnology, Kalasalingam University, Anand Nagar, India. After 2 month german classes in India and another 4 month german classes in Berlin I joined the lab in October 2010 for the period of one year. I am interested in studying the relationship between retinal glia and vasculature - in the next year I will concentrate on their interaction and roles during retinal regeneration.

Thursday, July 29, 2010

PEOPLE | PATRICK SCHÄFER

Patrick Schäfer  (Dipl.-Biol.)

Just received a PhD fellowship to start his thesis work in August 2010 in our lab.

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Wednesday, July 28, 2010

RETINA DEGENERATION

Retinal degeneration represents a group of blinding diseases that are increasingly impacting the health and well-being of affected patients. More than 150 genes are known and more being discovered causing retinal disorders upon mutation.   About 45 million people are blind worldwide (Europe 10 million, Germany 0.1 million). It is estimated that by 2020, over 76 million (www.vision2020.org) will suffer from vision loss or blindness due to age-related macular degen eration (AMD), the most common cause of retinal degeneration in the elderly. In Germany 1 million patients already suffer from high vision loss and about 2 million people have been diagnosed with AMD (1:10 above age 60).  AMD is anticipated to be epidemic by increasing 6-fold until 2025 (NIH, USA; BMBF Roadmap 2007).  Although loss of photoreceptors is the major reason for vision loss, in other retinal diseases, like glaucoma (ganglion cell loss), damage of other neurons is causative.  Development of various therapies targeting prevention, progression and repair is thus pressing and will not only contribute to maintain mobility, life quality and indepen dence, but also to reduce the social annual cost due to vision loss (>500 million in Germany today).
Frontiers of retinal research: Fortunately recent research provided remarkable proof-of-principle evidence on neuronal regeneration, retinal tissue engineering as well as neuronal replacement by cell transplantation in the retina opening up a new field of basic science of regenerative medicine. In the retina of adult mice a limited amount of neuronal regeneration by endogenous de-novo neurogenesis could be stimulated after neuron loss in vivo. Further, protocols for deriving retinal progenitor from human stem cell lines have been developed and derived photoreceptors integrate into adult mouse retina after transplantation.

Saturday, May 1, 2010

PEOPLE | KATI LÖFFLER

Kati Löffler (Dipl.-Biol)
Last year in April I finished my biology studies at the Georg August University in Göttingen with my major in neurobiology. I completed my diploma thesis “Intra-axonal dynamics of coexpressed guidance receptors during the neuromuscular development” at the European Neuroscience Institute in Göttingen (ENI-G) at the Developmental Neurobiology group of Dr. Till Marquardt.

NewImage.jpg

Sunday, April 4, 2010

visionclubbing

Gosh! What an eyedea?!

We started a visionclub on April 1st 2010 - no joking!
We have members investigating various aspects within eye research.
Our regular retina seminars with invited speakers, ORPS seminar, and…and...and
Join and participate!


www.visionclub.org


Friday, January 1, 2010

PEOPLE | TINA HOLDT

Tina Holdt (technician) - research technician, previously working at the Frauenhofer Institute for Molecular Biology and Applied Ecology.

Tuesday, December 1, 2009

LAB LOCATION 2010-2012

The new lab is located temporarily in the MTZ until the new building is finished at Tatzberg.


Dr. Mike O. Karl
Center for Regenerative Therapies Dresden (CRTD)
DFG Research Center and Cluster of Excellence
Tatzberg 47-51 01307 Dresden
Germany

http://www.crt-dresden.de/research/crtd-core-groups/karl/
Phone: +49-351-458-6445
Fax: +49-351-458-6303
mike.karl(att)crt-dresden.de

Mailbox /Postanschrift:
MTZ TU Dresden
Fiedlerstrasse 42
MOKALAB
ROOM A.00.64
01307 Dresden
Germany
moka logo blue 3D.png

PEOPLE | MIKE

Mike Karl  -  principal investigator

01.12.2009 - Very *excited* to start my own lab :)

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